Most expensive substance

Most expensive substance
Who
Antimatter
What
59,800,000,000,000 US dollar(s)
Where
Not Applicable
When
April 2025

The most valuable substance is antimatter, with an estimated value of $59.8 trillion (£49 tn) per gram, according to a 2025 report by BBC Science Focus.

The universe is made up of subatomic particles called matter, which exist alongside antimatter – particles with the same masses but opposite charges. Scientists believe antimatter could be used as fuel for interstellar travel.

The second and third most expensive substances, respectively, are nitrogen atom-based endohedral fullerenes ($134 m; £110 m per gram) and californium 252 ($25.6 m; £21 m per gram).